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Pre-diabetes: The Wake-Up Call You Didn't Know You Needed (But Definitely Do)

Dr. Tomader Ali (CIRTL(TF) ACRP(CP) PhD), Manager, Diabetes Education, Imperial College London Diabetes Centre
09 Jun 2025
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1. Introduction

We're sure you have heard of diabetes by now, or know someone who has been diagnosed with diabetes, and you are here for a reason. But what is Pre-diabetes?

At Imperial College London Diabetes & Endocrine Centre we can help you understand more about both prediabetes and diabetes and how to manage the condition for you or a loved one if diagnosed.

2. Prediabetes, its Progression and Complications

Prediabetes is an intermediate stage between normal glycemia (normal blood glucose levels) (1) and type 2 diabetes, where blood sugar levels are higher than normal but not yet high enough to be classified as diabetes. The term prediabetes is used to identify those individuals who are at risk for future diabetes. Prediabetes is also associated with a high burden of cardiometabolic risk factors and is associated with poor outcomes (2) overall in health, particularly long-term if left untreated, mainly because it can develop into Type 2 Diabetes.  Diabetes on the other hand is the condition where our bodies have trouble managing blood sugar levels (and by sugar we mean glucose again, just like in prediabetes) (3).

There are certain blood glucose ranges that are internationally set for our normal glucose range based on age, other diseases, complications, pregnancy and such factors (4). Our body usually can maintain elevated blood glucose levels (yes, even if we want a doughnut!), through complex biological mechanisms. Many hormones are involved, but one of the main hormones primarily responsible for this regulation, is insulin. When our bodies get to the stage where there is no more insulin endogenously (inside our bodies), your doctor will prescribe insulin therapy, and we have to inject it (exogenously, from outside the body) to inside of the body to replace the insulin we no longer have and to mimic natural hormone regulation of glucose in our bodies.

If left untreated, prediabetes might not feel like a big deal, but it’s setting you up for a future full of complications — some of which can be serious. Think heart disease, stroke, kidney damage, nerve problems, and vision issues. If you think of prediabetes as the ‘before’ picture, diabetes is the ‘after’ — so let’s act before it’s too late. But how do we know if we have prediabetes?

3. How Do I know I Have Prediabetes?

Signs & Symptoms

Here’s the tricky part. Unlike diabetes, there are often no symptoms. Prediabetes is a bit cheeky like that. There are subtle signs and signals that can be easily missed if you are not looking for them. For example:

  • Feeling extra thirsty
  • Peeing more than usual
  • Fatigue that makes you wonder if you’ve been hit by a bus
  • Blurred vision (yes, that's a thing!)

To make matters even more tricky, many people don’t experience any symptoms at all. So, the real key is getting tested. That’s the best way to find out!

Diagnosis

How do doctors figure out if you have prediabetes? The most important test is the measurement of your blood sugar (glucose). The three main tests are:

  1. Fasting Blood Sugar Test: This measures your blood sugar after an overnight fast. A level between 100 and 125 mg/dL means you’re in the prediabetes range.
  2. HbA1c Test: This shows your average blood sugar over the past two to three months. An HbA1c between 5.7% and 6.4% suggests prediabetes.
  3. Oral Glucose Tolerance Test (OGTT): After fasting, you drink a sugary beverage, and they test your blood sugar two hours later. A result between 140 and 199 mg/dL means prediabetes.

4. Treating and Managing Prediabetes

Let’s remember that prediabetes comes before diabetes, and it really wants us to pay attention to our body before we get diabetes permanently. While medication isn't usually necessary for prediabetes, some people might be prescribed Metformin (a diabetes medication) to help manage blood sugar (glucose). However, if you can make lifestyle changes and reverse prediabetes, you might avoid needing medication altogether.

It's like being at the top of a hill — you’re not quite at the bottom, but you’re very close to rolling down that slope, and if you catch ourself at the right point, and follow your treating physician’s advice and the clinical teams of Dieticians and Diabetes Educators, there is a good chance of treating prediabetes and stopping its progression to Type 2 diabetes.

So, prediabetes doesn’t have to become diabetes. You can hit the brakes before it’s too late and take charge of your health:

  • Track your blood sugar: Monitoring it can help you see how different foods and activities affect you.
  • Get moving and exercise: Aim for 30 minutes of physical activity most days of the week. Walking, swimming, or even dancing around your living room — it all counts.
  • Eat small, balanced meals: Don’t skip meals and avoid sugar spikes.
  • Eat healthier: Think fruits, veggies, whole grains, and lean protein.
  • Hydrate: Drink water over sugary drinks to keep your body running smoothly.
  • Lose weight: Losing 5-10% of your body weight can significantly reduce your risk.
  • Stress management: Chronic stress can impact blood sugar levels, so find your zen.

5. The Good News

While serious, it doesn’t mean you’re set to a future filled with needles and restrictive diets. In fact, if you catch it early, you can reverse it. Prediabetes is a physiological state that you can imagine is more like an early warning system for diabetes. It clearly says to us “Hey, pay attention!”

Prediabetes is not the end of the world. Sure, it can be a wake-up call, but it’s also a chance to make meaningful changes to your health. Many people with prediabetes manage to keep their blood sugar in check and prevent diabetes — and you can, too. With a little effort and a lot of positive choices, you can live a healthy, happy life without worrying about what might come next. For some people with prediabetes, early treatment as well as moderate lifestyle changes can actually return blood glucose (blood sugar) levels to a normal range, effectively preventing or delaying type 2 diabetes. Ask your doctor plenty of questions and listen to their answers. Increase your daily physical activity. Start eating healthy. And your life can be yours again (1).

6. Concluding Words

Don’t wait for a wake-up call. Make the changes now and start living your healthiest life!

At Imperial College London Diabetes & Endocrine Centre, we understand that there is so much information out there and we want to help improve the understanding of this information, and to ensure we translate this into accurate, correct and useful practical everyday life knowledge.

You have the power to stop prediabetes in its tracks!

References:

  1. ADA (Am. Diabetes Assoc.). 2020. 3. Prevention or delay of type 2 diabetes: Standards of Medical Care in Diabetes-2020. Diabetes Care 43 (Suppl. 1): S32–36 [DOI] [PubMed] [Google Scholar]
  2. https://diabetes.org/about-diabetes/diagnosis
  3. https://pmc.ncbi.nlm.nih.gov/articles/PMC8026645/#S1
  4. https://www.niddk.nih.gov/health-information/diabetes/overview/what-is-diabetes


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